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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6555 | K-Ras(G12C) inhibitor 12 | Apoptosis , Raf , Ras | |
K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C). | |||
T39099 | G12 | Ras 5-17 | |
G12 (Ras 5-17) is a wild-type Ras peptide composed of amino acids 5-17, specifically KLVVVGAGGVGKS. It can serve as a control in studies focused on mutant Ras peptides, like V12. | |||
T35689 | MTP 131 acetate | Others | |
MTP 131 is a mitochondria-targeted peptide antioxidant.1,2It localizes to the mitochondria and reducestert-butyl hydroperoxide-induced lipid peroxidation and apoptosis in SH-SY5Y cells when used at concentrations ranging... | |||
T24975 | 2MeSAMP | 2 MeS AMP bis-sodium,2-MeS-AMP bis-sodium,2MeSAMP bis-sodium | |
2MeSAMP is a P2Y(12) antagonist that works by inhibiting platelet activation through a P2Y(12)/G(i)-dependent mechanism. | |||
T83660 | 3(Z),6(Z),9(Z),12(Z),15(Z)-Octadecapentaenoic Acid | C18:5 n-3,C18:5(3Z,6Z,9Z,12Z,15Z),all-cis-3,6,9,12,15-Octadecapentaenoic Acid | |
3(Z),6(Z),9(Z),12(Z),15(Z)-Octadecapentaenoic acid, a microalgal polyunsaturated fatty acid (PUFA), is identified in G. kowalevskii and serves as a chemotaxonomic biomarker for microalgae and dinoflagellates. | |||
T62075 | HSV-1/HSV-2-IN-1 | ||
HSV-1/HSV-2-IN-1 is an HSV-1 and HSV-2 inhibitor that acts against HSV-1 (KOS) (EC50: 7.6 μM), HSV-2 (G) (EC50: 7.6 μM), HSV-1 TK-KOS ACVr (EC50: 4 μM) and cowpox virus (EC50: 12 μM). | |||
T37270 | 9(E),11(E)-12-nitro Conjugated Linoleic Acid | ||
9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combinat... | |||
T83697 | PAMP-12 (human, mouse, rat, porcine, bovine) TFA | Proadrenomedullin N-terminal 12 Peptide,PAMP (9-20) | |
Proadrenomedullin N-terminal 12 peptide (PAMP-12), an endogenous fragment originating from the adrenal medulla and spanning amino acids 9-20 of human PAMP-20, plays a role in causing hypotension. It functions as an agoni... | |||
T83926 | S-Geranylgeranyl-L-glutathione | GGG | |
S-Geranylgeranyl-L-glutathione acts as a ligand for the orphan G protein-coupled receptor (GPCR) P2RY8, displaying selective affinity by inducing internalization of P2RY8 in preference to the sphingosine-1-phosphate rece... | |||
T38077 | TLQP-21 TFA | ||
TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). T... | |||
T38167 | BE-24566B | ||
BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.1It is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = 1.56, 1.56, 1.56, 1.56, 3.13, an... | |||
T37272 | 9(S),12(S),13(S)-TriHOME | ||
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble ... | |||
T35560 | SAR502250 | ||
SAR502250 is a potent, selective, ATP-competitive, orally active, and brain-penetrant GSK3 inhibitor with a human GSK-3β IC50 value of 12 nM. It exhibits antidepressant-like activity and is being researched for potential... | |||
T35929 | O-Demethyl Apremilast | ||
O-Demethyl apremilast is an active metabolite of the phosphodiesterase 4 (PDE4) inhibitor apremilast .1It inhibits the activity of PDE4 isolated from U937 cells and LPS-induced TNF-α production in isolated human peripher... | |||
T38214 | 1-Deoxysphingosine (m18:1(4E)) | 1-Deoxysphingosine (m18:1(4E)) | |
1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine durin... | |||
T36000 | 3-Hydroxyterphenyllin | ||
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,... | |||
T38069 | Aquastatin A | ||
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC... | |||
T35683 | 2-deoxy-D-Glucose-13C6 | 2-deoxy-D-Glucose-13C6 | |
2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits h... | |||
T38100 | Betamethasone 21-phosphate (sodium salt hydrate) | ||
Betamethasone 21-phosphate is a synthetic glucocorticoid.1It prevents increases in macrophage and eosinophil numbers in bronchoalveolar lavage fluid (BALF) and decreases in blood leukocyte numbers in a guinea pig model o... | |||
T35893 | Rac-1,2-bis-Palmitoyl-3-chloropropanediol | ||
rac-1,2-bis-Palmitoyl-3-chloropropanediol is a 3-monochloropropane-1,2-diol (3-MCPD) ester.1It has been found as a contaminant in edible olive oils, with the lowest and highest concentrations in extra virgin and olive po... |